Xtinguish Plus

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2 lb. pail

Progressive Nutrition Veterinary CareXtinguish Plus
For Veterinary Use Only

Nutritional Supplement for Intestinal Health

PACKAGING: 2 lb. pail

Provides conditionally essential nutrients to horses during rehabilitation.

Many horses under veterinary supervision experience health-related problems, which result in digestive upset and unbalanced digestive ecosystem. This causes intestinal microbial breakdown. These situations demand immediate and effective support to restore the digestive
tract environment to its proper balance. Without adequate support, horses can suffer from inconsistent stool, laminitis, colic or death.

Xtinguish™ Plus from Progressive Nutrition VeterinaryCare™ is an innovative nutritional supplement containing selective nutrients that support the horse’s digestive ecosystem, returning it to normal, consequently avoiding detrimental and disastrous complications. Xtinguish™ Plus works on the entire digestive system from the stomach through the large intestine, providing conditionally essential nutrients to restore and maintain normal homeostatic balance.

Applications of Xtinguish™ Plus — to help ensure or restore a normal
digestive ecosystem

Conditions include:

  • Grain overload
  • Post-Operative colic surgery
  • Rehabilitation or stall rest after trauma
  • Overconsumption of lush spring pasture
  • Overheating/Fever
  • Normal intestinal micro flora death

Where does Xtinguish™ Plus work?

ChartStomach - Horses that are exposed to abnormal environmental conditions or are in situations of rehabilitation from surgery/trauma are at risk for gastric upset and ulcer symptoms. Xtinguish™ Plus contains Nutritional Gastric Technology, which has shown in research to reduce gastric upset by over 70% when compared to a control group8 (Figure 1). Nutritional Gastric Technology provides nutrients that initiate a cascade of cell-signaling events that continue well after the nutrients leave the stomach. Targeted nutrient feeding, including amino acids and polyamines which are effective even in the presence of inhibitors, restore epithelial cell unions and cover exposed membranes. Xtinguish™ Plus also contains nutrients that research has shown to improve gastric mucosal barrier, along with improved healing and lesion repair times.

Small and Large Intestine - The digestive tract contains large quantities of microbes, which are essential to normal gut health. Many situations can disrupt the homeostatic balance of microbes, causing microbial death and their resulting complications. Xtinguish™ Plus incorporates several nutrients, including Saccharomyces boulardii (Active Dried Yeast) and ImmunoLin*, that are shown in research to reduce the risks associated with microbial death and its possible disastrous results. Saccharomyces boulardii has been shown to be useful in horses suffering from enterocolitis1. Furthermore, Saccharomyces boulardii has shown great promise inhibiting Escherichia coli endotoxin via dephosphorylation3. ImmunoLin helps promote the immune response of gut-associated lymphoid tissues (GALT) to help reduce the absorption of harmful digestive contents, including the cell walls of dead bacterial.

Whole Body - During times of normal microbial fermentation, the horse produces enough Niacin and Thiamin to meets its own needs. Unfortunately, when the microbial population becomes compromised, this fermentation is disrupted along with the B-Vitamin production, leading to impaired recovery and overall health. Xtinguish™ Plus provides elevated levels of B-Vitamins to meet the essential metabolic and body function needed during certain situations.

  Improved
Gastric
Mucosal
Barrier
Endotoxin
Dephosphorylation
Enhanced
Healing and
Lesion Repair
Restore
Homeostatic
Gastrointestinal
Microbial
Environment
Improved GALT
Barrier Function
Anti Helicobacter
Properties
S. Boulardii1,3
X
X    
ImmunoLin2
  X  
L-Glutamine6
X
     
L-Glycine7
    X
Licorice Extract4,8
X
    X
Nutritional Gastric
Technology9
    X      
Aloe5     X      

Feeding Directions

 
Scoops per 1000 lbs of Body Weight
For optimum results, Xtinguish™ Plus should be provided every 6 hours prior to and after the onset of rehabilitation for up to 5 days
1 scoop (1/2 oz) 4 times daily
   
After 5 days, provide Xtinguish™ Plus twice daily
2 scoops (1 oz) twice daily
For the maintenance of an optimal gastric environment
1 scoop (1/2 oz) twice daily

 

Guaranteed Analysis

     

Crude Protein
Crude Fat
Crude Fiber

min
min
max

43.00%
00.50%
2.00%

Vitamin E
Thiamin
Niacin

min
min
min

180 IU /lb
4,000 mg/lb
4,000 mg/lb

 

Ingredients

L-Glutamine, L-Glycine, Licorice Extract, Dried Whey, Active Dried Yeast (Saccharomyces cerevisiae), Brewers Yeast Extract, Dried Egg Product, Serum Globulin, Whey Protein Concentrate, L-Tryptophan, Aloe Vera Gel Concentrate, Dried Lactobacillus acidophilus Fermentation Product, Dried Bifidobacterium thermophilum Fermentation Product, Dried Bifidobacterium longum Fermentation Product, Dried Enterococcus faecium Fermentation Product, Dried Bacillus subtillus Fermentation Product, Vitamin E Supplement, Thiamine Mononitrate, Niacin Supplement, Mineral Oil.

1Desrochers A, Dolente B, Roy M, Boston R, Carlisle S. Efficacy of Saccharomyces boulardii for treatment of horses with acute entercolitis. JAVMA 2005:227:954-959

2 Perez-Bosque A, Pelegri C, Vicarrio M, et al. Dietary plasma protein affects the immune response of diffuse gut associated lymphoid tissue in rats challenged with Staphylococcus aureus entertoxin B. J Nutr 2008; 138: 533-537

3 Buts J, Dekeyser N, Stilmant C, Delem E, Smets F, Sokal E. Saccharomyces boulardii produces in rat small intestine a novel protein phosphatase that inhibits Escherichia coli Endotoxin by Dephosphorylation. Ped Res 2006;60:24-29

4 Fukai T, Marumo A, Kaitou K, Kanada T, Terad S, Nomura T. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci 2002; 71:1449-1463

5 Borrelli F, Izzo A. The Plant Kingdom as a Source of Anti-Ulcer Remedies. Phytother. Res. 2000: 14: 581-591

6 Hagen S, Ohtani M, Zhou J, Taylor N, Rickman B, Blackburn G, Fox J. Inflammation and Foveolar Hyperplasia are Reduced by Supplementary Dietary Glutamine during Helicobacter pylori infection in mice. J. Nut. 2009; 139:912-918

7Minami M, Ando T, Hashikawa S, Torri K, Hasegawa T, Israel D, Ina K, Kusugami K, Goto H, Ohta M. Effect of Glycine on Helicobacter phylori in vitro. AntiMicrob. Agents Chemother. 2004: 48: 3782-3788

8Kassir Z. Endoscopic Controlled Trial of Four Drug Regimens in the Treatment of Chronic Duodenal Ulceration. Irish Med J. 1985; 78:153-155

9Mueller R, Trotter T, Cook D. Efffects of NGT on the Gastric Ulcer Score of 2 Year old and Older Horses in a Controlled Environment. www.Prognutrition.com. 2009.

*ImmunoLin is manufactured by Proliant, Inc. Learn more at www.ImmunoLin.com

 

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